gene 783 words KG: ELMO1
Contents

ELMO1 - Engulfment and Cell Motility 1

🧬 Gene Info
Gene SymbolELMO1
Full NameEngulfment and Cell Motility 1
AliasesPage for ELMO1, Page for ELMO1 Protein
Chromosome7p14.3
FunctionApoptotic Cell Clearance: ELMO1 mediates the recognition and engulfment of apoptotic cells by phagocytes [2]
Primary ExpressionMicroglia, Macrophages, Brain, Immune cells
Molecular Weight85 kDa
PathwaysAutophagy
UniProt IDQ9Y6I4
NCBI Gene ID2004
Ensembl IDENSG00000126603
OMIM606520
GeneCardsELMO1
Human Protein AtlasELMO1
Associated DiseasesParkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis
InteractionsAUTOPHAGY, LC3, LC3B
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (7)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

See Also (15)

ULK1 — UNC-51 Like Kinase 1
gene · KG edge: regulates
Neurodegeneration
disease · KG edge: implicated_in
ATG5 — Autophagy Related 5
gene · KG edge: regulates
Lysosome Dysfunction in Neurodegeneration
mechanism · KG edge: associated_with
MAP1LC3A Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

ATG5 regulates ELMO1
ELMO1 activates LC3
ELMO1 regulates ULK1
ELMO1 associated_with LYSOSOME
ELMO1 regulates INFLAMMATION
ELMO1 activates LC3B
ELMO1 associated_with PHAGOCYTOSIS
ELMO1 activates AUTOPHAGY
ELMO1 regulates Infection
ELMO1 regulates Inflammation

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