gene 1,942 words KG: GRID2
Contents

GRID2 — Glutamate Ionotropic Receptor Delta Type Subunit 2

🧬 Gene Info
Gene SymbolGRID2
Full NameGlutamate Ionotropic Receptor Delta Type Subunit 2
Protein TypeReceptor
FunctionGRID2 (Glutamate Receptor Ionotropic Delta 2), also known as GluRδ2 or GluD2, is a member of the delta glutamate receptor family with critical roles in cerebellar function, synaptic plasticity, and mo
Molecular Weight115 kDa
Ensembl IDENSG00000128283
GeneCardsGRID2
Human Protein AtlasGRID2
Protein Kinase C (PKC)Key mediator of LTD induction
CaMKIICalcium/calmodulin-dependent protein kinase II
MAP1BMicrotubule-associated protein involved in synaptic plasticity
Shank2Scaffold protein at postsynaptic密度
Associated DiseasesAls
InteractionsPDGFRA, GRIK3, SRC, NEURON, ERK, RAS
KG Connections39 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (2)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.41

Related Analyses (2)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (14)

Synapse Elimination in Neurodegeneration
mechanism · KG edge: transports
Ras-MAPK Signaling Pathway in Neurodegeneration
mechanism · KG edge: activates
erk-mapk-signaling-neurodegeneration
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
SRC Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

GRID2 inhibits PDGFRA
GRID2 activates GRIK3
GRID2 activates SRC
GRID2 transports GLUD2
GRID2 expressed_in GRID1
GRID2 expressed_in CBLN2
GRID2 expressed_in Rb
GRID2 expressed_in MAPK7
GRID2 expressed_in RIPK2
GRID2 expressed_in UHRF1