gene 2,012 words KG: KIF4A
Contents

KIF4A — Kinesin Family Member 4A

🧬 Gene Info
Gene SymbolKIF4A
Full NameKinesin Family Member 4A
ChromosomeXq13.1
Protein FamilyKinesin-4 family
Functionis a major axonal transport motor essential for neuronal function
Primary ExpressionBrain (neurons), proliferating cells
Molecular Weight140 kDa
Amino Acids1232 aa
Exons23
PathwaysCell Cycle, Epithelial-Mesenchymal Transition, ferroptosis
UniProt IDO95239
NCBI Gene ID22937
GeneCardsKIF4A
Human Protein AtlasKIF4A
N-terminal motor domain (1-400 aa)Contains the catalytic core with microtubule-binding site and ATPase activity
Associated Diseasesglioblastoma
InteractionsCANCER, CD8, CHMP4B, FERROPTOSIS, GBM, GLIOBLASTOMA
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Extracellular Vesicle Biogenesis Modulation
Score: 0.58
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (9)

Ferroptosis Validation in Parkinson's Disease
experiment · KG edge: activates
CD8 Gene
gene · KG edge: interacts_with
CHMP4B — Charged Multivesicular Body Protein 4B
gene · KG edge: activates
GLI Gene Family
gene · KG edge: activates
GPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: activates

Knowledge Graph (12 edges)

CD8 interacts_with KIF4A
UBIQUITIN interacts_with KIF4A
KIF20A associated_with KIF4A
HSP90AB1 associated_with KIF4A
KIF4A associated_with JUN
KIF4A interacts_with CHMP4B
CHMP4B activates KIF4A
GBM activates KIF4A
GPX4 activates KIF4A
KIF4A activates CHMP4B

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