| Gene Symbol | LETM1 |
| Full Name | Leucine Zipper and EF-Hand Containing Transmembrane Protein 1 |
| Chromosome | 4p16.3 |
| Function | encodes an essential mitochondrial inner membrane protein that plays critical roles in mitochondrial function, calcium homeostasis, and cellular metabolism. |
| Primary Expression | tissues with high metabolic demands, particularly the brain, cerebellum, heart, and skeletal mus |
| Molecular Weight | 81 kDa |
| Amino Acids | 739 aa |
| Exons | 14 |
| Pathways | oxidative stress response |
| Ensembl ID | ENSG00000168936 |
| GeneCards | LETM1 |
| Human Protein Atlas | LETM1 |
| Associated Diseases | AD, ALI, AMI, Cancer, Diabetes, Heart Failure |
| Interactions | OVERVIEW |
| KG Connections | 50 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |