| Gene Symbol | Lysosomal Trafficking Regulator |
| Chromosome | 1q42.1-q42.2 |
| Protein Type | Regulatory Protein, Lysosomal Function |
| Function | encodes a large cytosolic protein that plays critical roles in lysosomal function, vesicle trafficking, and autophagy. |
| Primary Expression | virtually all tissues, with highest expression in: |
| Subcellular Localization | LYST is primarily localized to: |
| Amino Acids | 801 aa |
| Pathways | Autophagy, Exocytosis |
| UniProt ID | Q99698 |
| NCBI Gene ID | 1130 |
| Ensembl ID | ENSG00000143669 |
| OMIM | 606897 |
| Lysosomes | Concentrated on lysosomal membranes |
| Late endosomes | Involved in endocytic trafficking |
| Cytoplasmic vesicles | Scattered vesicular pattern |
| Associated Diseases | neurodegeneration |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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