gene 712 words KG: MAP1S 2026-03-24
kind:genesection:genesstate:published
Contents

MAP1S - Microtubule Associated Protein 1S

🧬 Gene Info
Gene SymbolMAP1S
Full NameMicrotubule Associated Protein 1S
AliasesPage for MAP1S
Chromosome19p13.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight55 kDa
UniProt IDQ9Y2R9
NCBI Gene ID55130
Ensembl IDENSG00000131370
OMIM607358
GeneCardsMAP1S
Human Protein AtlasMAP1S
Associated DiseasesAls, Alzheimer, Ms
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (9)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · failed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Tau Protein
protein · KG edge: associated_with
Tau Consortium
organization · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with

Knowledge Graph (12 edges)

MAP1S associated_with PSP
MAP1S associated_with SP1
MAP1S associated_with APOE
MAP1S associated_with TAU
MAP1S associated_with KIF13A
MAP1S associated_with TRIM24
MAP1S associated_with STX6
MAP1S associated_with MAPT
MAP1S associated_with ALZHEIMER'S DISEASE
MAP1S associated_with ASTROCYTES