gene 569 words KG: STX6 2026-03-22
kind:genesection:genesstate:published
Contents

STX6 Gene

🧬 Gene Info
Gene SymbolSTX6
Protein TypeReceptor
FunctionSyntaxin 6 is a Q-SNARE protein localized primarily to the trans-Golgi network (TGN) and endosomes.
Subcellular Localizationprimarily to the *trans*-Golgi network (TGN) and endosomes
Ensembl IDENSG00000139334
GeneCardsSTX6
Human Protein AtlasSTX6
Associated DiseasesALS, Alzheimer, Alzheimer's disease, Ms, Parkinson's disease
KG Connections42 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53

Related Analyses (5)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Tau Protein
protein · KG edge: associated_with
Tau Consortium
organization · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with

Knowledge Graph (12 edges)

STX6 associated_with MAPT
STX6 therapeutic_target Creutzfeldt-Jakob Disease
STX6 causes TREM2
STX6 causes neurodegeneration
STX6 associated_with Alzheimer
STX6 associated_with Als
STX6 associated_with Ms
STX6 causes Alzheimer's disease
STX6 causes Parkinson's disease
STX6 causes ALS