| Gene Symbol | NOS3 |
| Full Name | Nitric Oxide Synthase 3 |
| Chromosome | 7q36 |
| Protein Type | Protein |
| Function | This is the basis for the therapeutic use of nitrates in cardiovascular disease [@katusic2009]. |
| Primary Expression | vascular endothelial cells where it catalyzes the production of nitric oxide (NO) from L-arginine |
| Amino Acids | 490 aa |
| Pathways | Mapk, autophagy pathway, complement cascade, phagocytosis |
| UniProt ID | Search UniProt |
| GeneCards | NOS3 |
| Human Protein Atlas | NOS3 |
| Associated Diseases | ALS, Alzheimer, Cancer, podocyte foot process effacement |
| Known Drugs/Compounds | rapamycin |
| Interactions | STING1, GLP1R, SREBF1, SIRT1, KDM6B, LC3 |
| KG Connections | 388 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |