CHMP6

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHMP6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CHMP6 is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, associated with. Associated with ALS, Als, Alzheimer. Connected to 42 entities in the SciDEX knowledge graph.

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graph TD
    CHMP6["<b>CHMP6</b>"]
    Alzheimer{"Alzheimer"}
    CHMP6 -->|"activates"| Alzheimer
    Dementia{"Dementia"}
    CHMP6 -->|"activates"| Dementia
    Als{"Als"}
    CHMP6 -->|"activates"| Als
    Ms{"Ms"}
    CHMP6 -->|"activates"| Ms
    Tauopathy{"Tauopathy"}
    CHMP6 -->|"activates"| Tauopathy
    Frontotemporal_Dementia{"Frontotemporal Dementia"}
    CHMP6 -->|"activates"| Frontotemporal_Dementia
    Ftd{"Ftd"}
    CHMP6 -->|"activates"| Ftd
    CHMP6 -->|"associated with"| Alzheimer
    CHMP6 -->|"associated with"| Ftd
    CHMP6 -->|"associated with"| Tauopathy
    ALS{"ALS"}
    CHMP6 -->|"activates"| ALS
    CHMP2B["CHMP2B"]
    CHMP6 -->|"activates"| CHMP2B
    RAB7A["RAB7A"]
    RAB7A -->|"regulates"| CHMP6
    RAB35["RAB35"]
    RAB35 -->|"regulates"| CHMP6
    CHMP2A["CHMP2A"]
    CHMP2A -->|"activates"| CHMP6
    CHMP2B -->|"activates"| CHMP6
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"activates"| CHMP6
    LYSOSOME["LYSOSOME"]
    LYSOSOME -->|"regulates"| CHMP6
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"activates"| CHMP6
    AND["AND"]
    AND -->|"activates"| CHMP6
    GENES["GENES"]
    GENES -->|"activates"| CHMP6
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"activates"| CHMP6
    DEMENTIA["DEMENTIA"]
    DEMENTIA -->|"activates"| CHMP6
    TAU["TAU"]
    TAU -->|"activates"| CHMP6
    style CHMP6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0