gene 2,954 words KG: CHMP6
Contents

CHMP6 Gene

🧬 Gene Info
Gene SymbolCHMP6
Full NameCharged Multivesicular Body Protein 6
Chromosome17q25.1
Protein TypeESCRT-III component
Primary ExpressionBrain, lung, testis, liver
Subcellular LocalizationEndosome, cytoplasm
Molecular Weight23 kDa
Amino Acids201 aa
PathwaysEscrt Pathway, Protein Aggregation, Tau Degradation, Tau Traffic
UniProt IDQ96FY2
NCBI Gene ID79170
Ensembl IDENSG00000115183
OMIM607986
GeneCardsCHMP6
Human Protein AtlasCHMP6
Associated DiseasesAls, Alzheimer, Ataxia, frontotemporal, Ftd, Infection
InteractionsActin, ALZHEIMER, ALZHEIMER'S DISEASE, APP, ATM, ATR
KG Connections100 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Extracellular Vesicle Biogenesis Modulation
Score: 0.58
Lysosomal Membrane Repair Enhancement
Score: 0.54
APOE-Dependent Autophagy Restoration
Score: 0.89
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67

Related Analyses (3)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
ATM Gene
gene · KG edge: inhibits
ATR Gene
gene · KG edge: inhibits
CHEK1 Gene
gene · KG edge: associated_with
CHMP2A
gene · KG edge: activates

Knowledge Graph (12 edges)

CHMP6 activates CHMP2B
CHMP6 activates CHMP2A
RAB7A regulates CHMP6
CHMP6 regulates RAB35
RAB35 regulates CHMP6
CHMP2A activates CHMP6
CHMP2B activates CHMP6
CHMP6 regulates RAB7A
CHMP6 activates TAU
CHMP6 regulates TAU

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.