gene 509 words KG: RNF13
Contents

RNF13 — Ring Finger Protein 13

🧬 Gene Info
Gene SymbolRNF13
Full NameRing Finger Protein 13
Chromosome3q25.1
Protein TypeLigase
Functionis a gene located on chromosome 3q25.
Primary ExpressionUbiquitously expressed; high expression in brain, heart, lung
Amino Acids516 aa
Exons8
UniProt IDO43573
NCBI Gene ID11320
Ensembl IDENSG00000082996
OMIM604555
GeneCardsRNF13
Human Protein AtlasRNF13
Associated DiseasesMs
InteractionsAPOPTOSIS, AUTOPHAGY, HO-1, NRF2, P62, TRIM21
KG Connections16 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

APOE-Dependent Autophagy Restoration
Score: 0.89
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: inhibits
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
NRF2 Gene
gene · KG edge: inhibits
NRF2 Activator Therapy
idea · KG edge: inhibits

Knowledge Graph (12 edges)

P62 inhibits RNF13
NRF2 inhibits RNF13
RNF13 inhibits NRF2
RNF13 inhibits P62
APOPTOSIS inhibits RNF13
AUTOPHAGY inhibits RNF13
HO-1 inhibits RNF13
RNF13 therapeutic_target Ischemia
RNF13 associated_with Ms
RNF13 therapeutic_target Stroke

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