TRIM21

Understanding Entity Pages

This page aggregates everything SciDEX knows about TRIM21: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TRIM21 is a concept in neurodegeneration research. Key relationships include: activates, interacts with, regulates. Associated with AD, ALI, AMI. Connected to 176 entities in the SciDEX knowledge graph.

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graph TD
    TRIM21["TRIM21"]
    TRIM21 -->|"interacts"| Carcinoma["Carcinoma"]
    TRIM21 -->|"ubiquitinates"| SQSTM1["SQSTM1"]
    TRIM21 -->|"interacts"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    TRIM21 -->|"interacts"| Dementia["Dementia"]
    TRIM21 -->|"interacts"| OPTN["OPTN"]
    TRIM21 -->|"activates"| NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    TRIM21 -->|"interacts"| ACTB["ACTB"]
    TRIM21 -->|"interacts"| ALS["ALS"]
    TRIM21 -->|"interacts"| CALCOCO2["CALCOCO2"]
    TRIM21 -->|"interacts"| NBR1["NBR1"]
    SQSTM1 -->|"binds"| TRIM21
    C9ORF72["C9ORF72"] -->|"interacts"| TRIM21
    LC3["LC3"] -->|"interacts"| TRIM21
    P62["P62"] -->|"interacts"| TRIM21
    FUS["FUS"] -->|"interacts"| TRIM21
    UBIQUITIN["UBIQUITIN"] -->|"regulates"| TRIM21
    SMCR8["SMCR8"] -->|"interacts"| TRIM21
    NDP52["NDP52"] -->|"interacts"| TRIM21
    CALCOCO2 -->|"interacts"| TRIM21