| Gene Symbol | ROBO1 |
| Full Name | Roundabout Guidance Receptor 1 |
| Chromosome | 3p12.3 |
| Protein Type | Receptor |
| Function | encodes a transmembrane receptor that plays critical roles in axon guidance and cell migration during nervous system development |
| Primary Expression | the midline, provides repulsive cue |
| Amino Acids | 1657 aa |
| UniProt ID | [Q9Y6N7](https://www.uniprot.org/uniprot/Q9Y6N7) |
| Ensembl ID | ENSG00000169855 |
| OMIM | 606362 |
| GeneCards | ROBO1 |
| Human Protein Atlas | ROBO1 |
| 5 Immunoglobulin (Ig) domains | Mediate ligand binding and protein interactions |
| 3 Fibronectin type III (FNIII) repeats | Provide structural support and interaction surfaces |
| Single-pass transmembrane helix | Anchors the receptor in the plasma membrane |
| Associated Diseases | Als, Cardiac |
| Interactions | UBIQUITIN |
| KG Connections | 26 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |