gene 892 words KG: SCN2B 2026-03-21
kind:genesection:genesstate:published
Contents

SCN2B Gene - Sodium Channel Beta Subunit

🧬 Gene Info
Gene SymbolSCN2B
Full NameSodium Voltage-Gated Channel Beta Subunit 2
AliasesPage for SCN2B Gene
Chromosome11q23.3
Functionis a network-stability modifier rather than a single-cause disease gene.
Molecular Weight24 kDa
UniProt IDO60939
NCBI Gene ID6327
Ensembl IDENSG00000177017
OMIM601327
GeneCardsSCN2B
Human Protein AtlasSCN2B
ProteinSCN2B Protein
Associated DiseasesInflammation
InteractionsSCN8A, GRM5, FGF13, CDK5R2, SLC17A7, STAT1
KG Connections61 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

See Also (6)

APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: therapeutic_target
ISG15 — Interferon-Stimulated Gene 15
gene · KG edge: associated_with
GRM5 Gene - Metabotropic Glutamate Receptor 5
gene · KG edge: associated_with
FGF13 — Fibroblast Growth Factor 13
gene · KG edge: associated_with
CDK5R2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SCN2B therapeutic_target CDK5R2
SCN2B therapeutic_target ISG15
SCN2B associated_with STAT1
SCN2B associated_with ISG15
SCN2B associated_with SCN8A
SCN2B associated_with FGF13
SCN2B associated_with SLC17A7
SCN2B associated_with CDK5R2
SCN2B associated_with GRM5
SCN2B interacts_with SCN8A