gene 851 words KG: SCN8A
Contents

SCN8A Gene - Nav1.6

🧬 Gene Info
Gene SymbolSCN8A
Full NameSodium Voltage-Gated Channel Alpha Subunit 8
AliasesSCN8A/Nav1.6 gene
Chromosome12q13.13
FunctionThe SCN8A gene encodes the alpha subunit of the voltage-gated sodium channel Nav1.6.
Primary ExpressionBrain, Cerebellum, Hippocampus, Cortex
Molecular Weight260 kDa
PathwaysAkt
UniProt IDQ9UQD0
NCBI Gene ID6334
Ensembl IDENSG00000175550
OMIM600402
GeneCardsSCN8A
Human Protein AtlasSCN8A
Associated DiseasesAtaxia, Inflammation, Ms, Parkinson
InteractionsCDK5R2, CREB, ERK, FGF13, GRM5, ISG15
KG Connections98 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

GBA (Redirect)
redirect · KG edge: therapeutic_target
Genes
index · KG edge: associated_with
AKT1 Gene
gene · KG edge: regulates
CDK5R2 Gene
gene · KG edge: associated_with
CREBBP Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

DOCK2 associated_with SCN8A
SCN8A therapeutic_target AKT1
SCN8A therapeutic_target SCN2A
SCN8A therapeutic_target SCN4A
SCN8A therapeutic_target GBA
TRPA1 inhibits SCN8A
SRC inhibits SCN8A
SCN8A regulates AKT1
SCN8A regulates TRPM3
SCN8A regulates CREBBP

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