| Gene Symbol | IDE |
| Aliases | Page for IDE Gene |
| Chromosome | 10q23.33 |
| Protein Type | Protease |
| Function | Peptide hydrolysis, amyloid clearance |
| Molecular Weight | 110 kDa |
| Amino Acids | 1019 aa |
| Pathways | Oxidative Stress |
| NCBI Gene ID | 3416 |
| GeneCards | IDE |
| Human Protein Atlas | IDE |
| Amyloid-beta degradation | Primary enzyme responsible for clearing Abeta in the brain |
| Insulin metabolism | Regulates insulin signaling through peptide degradation |
| Proteostasis | Maintains cellular protein quality control |
| Disease associations | Alzheimer's disease, Parkinson's disease, Type 2 diabetes |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease, Diabetes, Insulin Resistance |
| Known Drugs/Compounds | metformin |
| Interactions | ACE, ACE2, AD, ADAM10, AKT, ALZHEIMER |
| SciDEX Hypotheses | Personalized Microbiome Restoration Based on Indiv |
| KG Connections | 254 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
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