concept

IL4R

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL4R: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections

0Hypotheses

0Analyses

20Outgoing

13Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	IL4R
Key Genes/Proteins	IL-13, CLDN1, S100A8, IFNG, IL31, RNA
Related Diseases	Als, Atherosclerosis, ALS, Inflammation
Related Pathways	Th2 Pathway

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    IL4R["IL4R"]
    IL4R -->|"involved_in"| Th2_Pathway["Th2 Pathway"]
    IL4R -->|"expressed in"| Als["Als"]
    IL4R -->|"expressed in"| Atherosclerosis["Atherosclerosis"]
    IL4R -->|"expressed in"| ALS["ALS"]
    IL4R -->|"expressed in"| Inflammation["Inflammation"]
    IL4R -->|"expressed in"| IL_13["IL-13"]
    IL4R -->|"expressed in"| CLDN1["CLDN1"]
    IL4R -->|"expressed in"| S100A8["S100A8"]
    IFNG["IFNG"] -->|"expressed in"| IL4R
    IL22["IL22"] -->|"expressed in"| IL4R
    RNA["RNA"] -->|"expressed in"| IL4R
    S100A9["S100A9"] -->|"expressed in"| IL4R
    IL31["IL31"] -->|"expressed in"| IL4R
    GENES["GENES"] -->|"expressed in"| IL4R
    INFLAMMATION["INFLAMMATION"] -->|"expressed in"| IL4R
    CLDN1 -->|"expressed in"| IL4R

Outgoing (20)

Target	Relation	Type	Str
Th2 Pathway	involved_in	pathway	0.80
Als	expressed_in	disease	0.65
Atherosclerosis	expressed_in	disease	0.65
ALS	expressed_in	disease	0.65
Inflammation	expressed_in	disease	0.65
IL-13	expressed_in	gene	0.60
CLDN1	expressed_in	gene	0.60
S100A8	expressed_in	gene	0.60
IFNG	expressed_in	gene	0.60
IL31	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
S100A9	expressed_in	gene	0.60
Interleukin	expressed_in	protein	0.60
IL22	expressed_in	gene	0.60
INFLAMMATION	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
Il-1	expressed_in	protein	0.60
LOR	expressed_in	gene	0.60
microglia	expressed_in	cell_type	0.55

Incoming (13)

Source	Relation	Type	Str
Tralokinumab	downregulates	drug	0.90
IFNG	expressed_in	gene	0.60
IL22	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
S100A9	expressed_in	gene	0.60
IL31	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
INFLAMMATION	expressed_in	gene	0.60
CLDN1	expressed_in	gene	0.60
S100A8	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
IL-13	expressed_in	gene	0.60
CCL26	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found