gene 779 words KG: IRF1 2026-03-24
kind:genesection:genesstate:published
Contents

IRF1 Gene - Interferon Regulatory Factor 1

🧬 Gene Info
Gene SymbolIRF1
Full NameInterferon Regulatory Factor 1
AliasesPage for IRF1 Gene, Page for IRF1 Protein
Chromosome5q31.1
Protein TypeTranscription Factor
Functionis a transcription factor encoded by the IRF1 gene located on chromosome 5q31.
Molecular Weight36 kDa
Amino Acids325 aa
PathwaysAutophagy, Cell Cycle, Complement, Immune Response, Immunotherapy
UniProt IDP04855
NCBI Gene ID3659
Ensembl IDENSG00000125347
OMIM147575
GeneCardsIRF1
Human Protein AtlasIRF1
Associated DiseasesALS, Inflammation, Ms, Neuroinflammation
InteractionsCIITA, ATG5, CD8, NPM1, CALCOCO2, NDP52
KG Connections265 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

IRF1 interacts_with NPM1
IRF1 activates CIITA
IRF1 inhibits ATG5
IRF1 activates CD8
IRF1 activates NPM1
IRF1 inhibits CALCOCO2
IRF1 inhibits NDP52
IRF1 activates TNF
IRF1 activates STAT1
IRF1 regulates RB1CC1