| Gene Symbol | CIITA |
| Aliases | MHC2TA, NLRA |
| Chromosome | 16p13.13 |
| Protein Type | Transcriptional coactivator |
| Function | ### MHC Class II Expression |
| Primary Expression | non-immune cells:
- Endothelial cells: Can express MHC class II in response to IFN-γ
- Tumor cells: Sometimes expressed in cancer cells
- Ne |
| Molecular Weight | 125 kDa |
| Amino Acids | 1130 aa |
| Pathways | Autophagy, Immune Response, Inflammasome, Mitophagy |
| UniProt ID | P33076 |
| NCBI Gene ID | 4261 |
| Ensembl ID | ENSG00000179583 |
| GeneCards | CIITA |
| Human Protein Atlas | CIITA |
| Official Name | Class II Major Histocompatibility Complex Transactivator |
| Associated Diseases | neurodegeneration |
| Interactions | CD8, NPM1, IRF1, NLRC5, CREB1, JAK1 |
| KG Connections | 60 knowledge graph edges |
| Databases | GeneCardsHPASTRING |