| Gene Symbol | NEFL |
| Full Name | Neurofilament Light Chain |
| Chromosome | 8p21.2 |
| Function | These dimers associate in an antiparallel, staggered manner to form tetramers, which then laterally associate into protofilaments and mature 10-nm intermediate filaments. |
| Primary Expression | Motor Neurons, Cortical Neurons, Peripheral Nerves, All Neurons (ubiquitous) |
| Molecular Weight | 62 kDa |
| Amino Acids | 543 aa |
| Exons | 4 |
| Pathways | Axonal Transport |
| UniProt ID | P07196 |
| NCBI Gene ID | 4747 |
| Ensembl ID | ENSG00000277586 |
| OMIM | 162280 |
| GeneCards | NEFL |
| Human Protein Atlas | NEFL |
| Associated Diseases | Alzheimers_disease |
| Interactions | ALS, AMYOTROPHIC LATERAL SCLEROSIS, BCL2, BNIP3L, C9ORF72, CNR1 |
| SciDEX Hypotheses | Plasma NfL Elevation Secondary to BBB-Associated T Plasma NfL Elevation Secondary to BBB-Associated T |
| KG Connections | 197 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!