gene 759 words KG: PGK1
Contents

PGK1 Gene

🧬 Gene Info
Gene SymbolPGK1
Full NamePhosphoglycerate Kinase 1
ChromosomeXq21.1
Protein TypeEnzyme
FunctionPGK1 catalyzes the reversible conversion of 1,3-bisphosphoglycerate (1,3-BPG) to 3-phosphoglycerate (3-PG), generating ATP
Primary Expressionbrain tissue
Molecular Weight44.6 kDa
Amino Acids417 aa
PathwaysGlycolysis, Mtor
UniProt IDP00558
NCBI Gene ID5230
Ensembl IDENSG00000102144
OMIM311800
GeneCardsPGK1
Human Protein AtlasPGK1
Associated DiseasesAls, Cancer, Carcinoma, Glioblastoma, Tumor
Known Drugs/Compoundslevodopa, terazosin, Terazosin
InteractionsAPOE3, APOE4, ATG14L, ATP, AUTOPHAGY, CANCER
KG Connections81 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

PGK1 produces methylglyoxal
YWHAZ associated_with PGK1
VDAC1 associated_with PGK1
HNRNPA1 associated_with PGK1
PGK1 associated_with PTK2
TP53 therapeutic_target PGK1
GAIN therapeutic_target PGK1
PGK1 regulates BECLIN1
PGK1 regulates MTOR
PGK1 expressed_in PARK7

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