gene 519 words KG: BECLIN1 2026-03-24
kind:genesection:genesstate:published
Contents

BECN1 Gene

🧬 Gene Info
Gene SymbolBECLIN1
Full NameBECN1
Protein TypeGene
Functionis a gene/protein encoding a key neuronal protein involved in synaptic function, signal transduction, and cellular homeostasis
PathwaysApoptosis, Autophagy, Mtor, Oxidative Stress
NCBI Gene IDSearch NCBI
GeneCardsBECLIN1
Human Protein AtlasBECLIN1
Associated DiseasesAls, Alzheimer, Cancer, Colorectal Cancer, Glioblastoma, Inflammation
InteractionsMTOR, SOX9, AKT, RANK, RANKL, BCL2
KG Connections623 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (23)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
Circadian Clock-Autophagy Synchronization
Score: 0.55
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.47
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (15)

Alzheimer Indonesia
institution · KG edge: associated_with
APAF1 Gene
gene · KG edge: regulates
AMBRA1 Gene
gene · KG edge: activates
AKT1 Gene
gene · KG edge: activates
ADRB2 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

BECLIN1 associated_with BCL2
BECLIN1 associated_with TAAR1
BECLIN1 associated_with SIGMAR1
BECLIN1 associated_with MYD88
BECLIN1 associated_with PUMA
BECLIN1 associated_with P62
BECLIN1 activates MTOR
BECLIN1 activates SOX9
BECLIN1 activates AKT
BECLIN1 associated_with LC3