protein 717 words KG: ATG9A 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

ATG9A Protein

🔬 Protein Info
Gene SymbolATG9A
AliasesATG9A protein
Chromosome2p24.1
Protein FamilyATG9 family
FunctionMembrane Source: Provides lipids for phagophore expansion
Subcellular LocalizationTrans-Golgi network, Endosomes, Plasma membrane, Autophagosomes
Molecular Weight139 kDa (939 amino acids)
Amino Acids790 aa
PathwaysAutophagy, Mitochondrial Function, Mitophagy, Nf-Κb, Stem Cell
UniProt ID Q7Z418
GeneCardsATG9A
Human Protein AtlasATG9A
Protein NameAutophagy Protein 9A
GeneATG9A
PDB ID6J5N
Associated DiseasesMs
InteractionsBECN1, LC3, FIP200, ARAF, BECLIN1, ATG12
KG Connections176 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

APOE-Dependent Autophagy Restoration
Score: 0.61
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.43
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (9)

Packard Center for ALS Research
institution · KG edge: regulates
ATG5 — Autophagy Related 5
gene · KG edge: activates
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: activates
ATG13 — Autophagy Related 13
gene · KG edge: interacts_with
ATG12 — Autophagy Related 12
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ATG9A regulates TBK1
ATG9A regulates PTEN
ATG9A regulates PINK1
ATG9A regulates PARKIN
ATG9A regulates RAB7A
ATG9A regulates BNIP3L
ATG9A inhibits BECN1
ATG9A co-localizes SYNAPTOPHYSIN
ATG9A protects_against TNFR1
ATG9A interacts_with LC3