protein 746 words KG: FOSPROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

FOS Protein

🔬 Protein Info
Gene SymbolFOS
Full NameFBJ Murine Osteosarcoma Viral Oncogene Homolog
Chromosome14q24.3
Protein TypeTranscription Factor
FunctionFOS is an immediate-early gene encoding a leucine zipper transcription factor.
Subcellular Localization</b></td><td>Nucleus</td></tr>
Molecular Weight40.6 kDa
PathwaysImmune Response, Neurogenesis, Nf-Kb, Nf-Κb, Synaptic Plasticity
UniProt IDP01100
NCBI Gene ID2353
Ensembl IDENSG00000170345
OMIM164810
GeneCardsFOS
Human Protein AtlasFOS
Associated DiseasesAls, Alzheimer, Atherosclerosis, Cancer, Ischemia, Ms
Known Drugs/Compoundspokeweed mitogen
InteractionsSRC, JUN, STAT3, CAT, JUND, JUNB
KG Connections500 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.41
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.41
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (8)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses