| Gene Symbol | GABA |
| Full Name | A Receptor Alpha 1 Protein |
| Chromosome | 12p12.3 |
| Function | is a hallmark of neurodegeneration. |
| Primary Expression | hippocampus, cortex, cerebellum, thalamus, hypothalamus |
| Amino Acids | 602 aa |
| Exons | 14 |
| Pathways | GABAergic Signaling |
| GeneCards | GABA |
| Human Protein Atlas | GABA |
| Subunit composition | Typically 2 α subunits, 2 β subunits, and 1 γ/δ subunit |
| α1-containing receptors | Most abundant (~60% of all GABA-A receptors) |
| Benzodiazepine binding site | Located at the α1/γ2 interface |
| Alternative splicing | Multiple splice variants affect trafficking and function |
| Fast inhibitory neurotransmission | Chloride influx causes neuronal hyperpolarization |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease |
| Known Drugs/Compounds | rapamycin |
| Interactions | ABCA7, ACTB, Actin, Akt, AKT, AKT1 |
| KG Connections | 1370 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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