| Gene Symbol | MAP1LC3B |
| Full Name | Microtubule-associated proteins 1A/1B light chain 3B |
| Aliases | LC3B |
| Chromosome | 16q24.2 |
| Function | MAP1LC3B encodes LC3B, a key protein in the autophagy pathway. |
| Primary Expression | Ubiquitous, high in brain (neurons and glia), liver, heart, skeletal muscle |
| Subcellular Localization | ** Cytosol, autophagosome membrane, lysosome [@khandelwal2021] |
| Molecular Weight | 14.5 kDa |
| Amino Acids | 125 aa |
| Pathways | Apoptosis, Autophagy, Immune Response, Innate Immunity, Mapk |
| UniProt ID | Q9GZQ8 |
| NCBI Gene ID | 81631 |
| Ensembl ID | ENSG00000140941 |
| OMIM | 609605 |
| GeneCards | MAP1LC3B |
| Human Protein Atlas | MAP1LC3B |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | rapamycin, cocaine, LPS |
| Interactions | GBA, FUNDC1, AMBRA1, PINK1, BCL2L13, NLRP3 |
| KG Connections | 1993 knowledge graph edges |
| Databases | GeneCardsHPASTRING |