protein 620 words KG: MLKLPROTEIN 2026-03-14
kind:proteinsection:proteinsstate:published
Contents

MLKL Protein

🔬 Protein Info
Gene SymbolMLKL
Chromosome16q23.1
Protein FamilyRHIM domain-containing pseudo-kinase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight~54 kDa
Amino Acids480 aa
Exons10
PathwaysAkt, Apoptosis, Autophagy, Cell Division, Ferroptosis
UniProt IDQ8TBX5
NCBI Gene ID83568
Ensembl IDENSG00000147854
GeneCardsMLKL
Human Protein AtlasMLKL
Protein NameMixed Lineage Kinase Domain-Like
Chromosome Location3q25.1
Associated DiseasesALS, Alzheimer's disease, DEMYELINATION, Inflammation, Ischemia
Known Drugs/CompoundsRAPAMYCIN, METFORMIN, rapamycin, metformin, Necrosulfonamide, HSYA
InteractionsDEPTOR, HMGB1, EGF, MLST8, RICTOR, MTOR
KG Connections1115 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph