| Gene Symbol | NEIL2 |
| Full Name | Nei Endonuclease VIII-Like 2 |
| Chromosome | 8p23.1 |
| Protein Family | FPG/Nei DNA Glycosylase Family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain (cortex, hippocampus), Testis, Liver, Kidney |
| Subcellular Localization | Nucleus, Mitochondria |
| Molecular Weight | 40 kDa |
| UniProt ID | Q96S44 |
| Ensembl ID | ENSG00000179119 |
| GeneCards | NEIL2 |
| Human Protein Atlas | NEIL2 |
| Fpg/Nei Domain | Catalytic core with the helix-hairpin-helix (HhH) motif |
| Iron-Sulfur Cluster Binding Site | 4Fe-4S cluster for structural stability |
| Proline Insertion | Unique proline-rich insertion that may contribute to substrate specificity |
| Interactions | ABCB1, BRAF, CANCER, ERK, NEIL1, NEIL3 |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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