| Gene Symbol | BRAF |
| Full Name | B-Raf Proto-Oncogene, Serine/Threonine Kinase |
| Aliases | RAF kinase in MAPK signaling |
| Protein Family | RAF serine/threonine kinases |
| Protein Type | Serine/Threonine Kinase |
| Function | BRAF is a serine/threonine-protein kinase that serves as a key intermediate in the RAS-RAF-MEK-ERK signaling cascade. |
| Molecular Weight | 84.5 kDa |
| Amino Acids | 766 aa |
| Pathways | MAPK, mapk |
| UniProt ID | [P15056](https://www.uniprot.org/uniprot/P15056) |
| GeneCards | BRAF |
| Human Protein Atlas | BRAF |
| Associated Diseases | AD, ALS, AMELOBLASTOMA, Cancer |
| Known Drugs/Compounds | encorafenib + cetuximab, SORAFENIB, TRAMETINIB, dabrafenib |
| Interactions | PI3K, ERK1, GNAQ, STX17, GNA11, AKT |
| KG Connections | 610 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |