| Gene Symbol | OPTINEURIN |
| Full Name | Optineurin |
| Chromosome | 10p13 |
| Protein Family | Selective autophagy receptors (SQSTM1-like) |
| Protein Type | Adaptor Protein |
| Function | The UBAN domain recognizes ubiquitin chains on mitochondria, while the LIR motif recruits autophagosomes. |
| Molecular Weight | ~67 kDa |
| Amino Acids | 577 |
| Pathways | Amyloid, Autophagy, Myelination, Necroptosis, Oxidative Stress |
| UniProt ID | Q96CV9 |
| GeneCards | OPTINEURIN |
| Human Protein Atlas | OPTINEURIN |
| Associated Diseases | ALS, Alzheimer, Amyotrophic Lateral Sclerosis, Dementia, Frontotemporal Dementia |
| Interactions | TOLLIP, NDP52, BECN1, G3BP1, SMCR8, SNCAIP |
| KG Connections | 1230 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |