protein 646 words KG: OPTNPROTEIN 2026-03-27
kind:proteinsection:proteinsstate:published
Contents

OPTN Protein (Optineurin)

🔬 Protein Info
Gene SymbolOPTN
Full NameOptineurin
Chromosome10p13
Protein TypeAdaptor Protein
Functionis a 66 kDa coiled-coil domain-containing protein encoded by the OPTN gene on chromosome 10p13.
Primary ExpressionMotor cortex, Spinal cord, Retina, Brain
Molecular Weight66 kDa
Amino Acids577 aa
PathwaysAkt, Amyloid, Apoptosis, Autophagy, Immune Response
UniProt IDQ96CV9
NCBI Gene ID10133
Ensembl IDENSG00000123240
OMIM602432
GeneCardsOPTN
Human Protein AtlasOPTN
Associated DiseasesAD, ALI, ALS, AMI, AUTOPHAGY, AXONAL DEGENERATION
Known Drugs/CompoundsDEFERIPRONE, RAPAMYCIN, dimethyl fumarate, rapamycin, loganin
InteractionsRIPK1, ULK1, SMCR8, CALCOCO2, LC3, BECN1
KG Connections2473 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph