| Gene Symbol | PPP3CB |
| Aliases | PPP3CBPROTEIN |
| Chromosome | 2p22.1 |
| Protein Family | Ser/Thr protein phosphatase 2B (PP2B) |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain (hippocampus, cortex), testis |
| Subcellular Localization | Cytoplasm, nucleus (upon activation) |
| Molecular Weight | ~59 kDa |
| Amino Acids | 524 aa |
| Pathways | Autophagy, Chaperone, Mtor, Tdp-43, autophagy pathway |
| UniProt ID | P16234 |
| NCBI Gene ID | 5519 |
| Ensembl ID | ENSG00000107738 |
| GeneCards | PPP3CB |
| Human Protein Atlas | PPP3CB |
| Associated Diseases | ALS, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma |
| Known Drugs/Compounds | rapamycin |
| Interactions | ATG10, CALCINEURIN, ATG12, TFEB, MTOR, LGALS3 |
| KG Connections | 191 knowledge graph edges |
| Databases | GeneCardsHPASTRING |