protein 850 words KG: RIPK2PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

RIPK2 Protein

🔬 Protein Info
Gene SymbolRIPK2
Full NameReceptor-Interacting Serine/Threonine Kinase 2
Chromosome8q21.3
Protein TypeSerine/Threonine Kinase
Functionis a critical serine/threonine kinase that serves as the primary signaling adaptor for NOD1 and NOD2 pattern recognition receptors.
Subcellular Localization</strong></td><td>Cytoplasm, Cytoskeleton</td></tr>
Molecular Weight61 kDa
Amino Acids540 aa
PathwaysNF-κB, MAPK, MAPK signaling
UniProt IDQ9Y2K6
NCBI Gene ID8767
Ensembl IDENSG00000137275
OMIM603614
GeneCardsRIPK2
Human Protein AtlasRIPK2
Associated DiseasesAlzheimer, Amyotrophic Lateral Sclerosis, Cancer, Colorectal Cancer, IBD, Inflammatory Bowel Disease
Known Drugs/Compoundsrapamycin
InteractionsIFIH1, GNAI1, ATG16L1, GNG2, GNAI2, NOD2
KG Connections326 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph