| Gene Symbol | SYN1PROTEIN |
| Full Name | Synapsin I |
| Protein Type | Protein |
| Function | is a neuronal phosphoprotein that plays a crucial role in regulating synaptic transmission and synaptic vesicle dynamics at the presynaptic terminal. |
| Molecular Weight | 80 kDa |
| UniProt ID | Search UniProt |
| GeneCards | SYN1PROTEIN |
| Human Protein Atlas | SYN1PROTEIN |
| C-terminal Domain | Rich in proline residues, facilitating interactions with actin filaments and other cytoskeletal elements through its ability to bind F-actin |
| Linker Region | Provides structural flexibility and mediates protein-protein interactions essential for vesicle clustering |
| Phosphorylation Sites | Contains multiple consensus sequences for phosphorylation by various kinases, enabling rapid modulation of function in response to neuronal activity[^4] |
| Associated Diseases | aging, Als, Alzheimer, Alzheimer'S Disease |
| Known Drugs/Compounds | rapamycin, RAPAMYCIN |
| Interactions | ACTB, Actin, AD, ADAM10, AKT, ALZHEIMER |
| KG Connections | 501 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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