| Gene Symbol | SYP |
| Full Name | Synaptophysin |
| Chromosome | Xp11.23 |
| Function | Synaptophysin is the most abundant synaptic vesicle membrane protein, constituting up to 10% of all synaptic vesicle proteins. |
| Primary Expression | Brain (cortex, hippocampus), cerebellum, retina, neuroendocrine cells |
| Molecular Weight | 38 kDa |
| Amino Acids | 316 aa |
| Pathways | Amyloid, Apoptosis |
| UniProt ID | P21579 |
| Ensembl ID | ENSG00000100391 |
| GeneCards | SYP |
| Human Protein Atlas | SYP |
| Application | Utility |
| Synaptic integrity | Diagnose/ stage AD |
| Disease progression | Monitor decline |
| Associated Diseases | ALS, Epilepsy, Ms |
| Interactions | IL6, BDNF, GFAP, RAB5, GDI1, RAB3A |
| KG Connections | 315 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |