protein 650 words KG: TRPV1 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

TRPV1 Protein

🔬 Protein Info
Gene SymbolTRPV1
Full NameTRPV1
Chromosome17p13.2
Protein TypeProtein
FunctionTRPV1 is a capsaicin-activated ion channel that responds to heat and pain stimuli.
Primary Expressionsensory neurons (dorsal root ganglion, trigeminal ganglion), where it functions as a polymodal nociceptor activated by[@caterina2
PathwaysAutophagy
UniProt ID[Q9Y5Q1](https://www.uniprot.org/uniprotkb/Q9Y5Q1/entry)
GeneCardsTRPV1
Human Protein AtlasTRPV1
Associated DiseasesCancer, Ovarian Cancer
InteractionsTERT, GPX4, APOE4, TRPA1, FERROPTOSIS, TAUOPATHY
KG Connections231 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (10)

Purinergic Signaling Polarization Control
Score: 0.55
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
LRP1-Dependent Tau Uptake Disruption
Score: 0.44
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44

Related Analyses (9)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (7)

Alzheimer Indonesia
institution · KG edge: activates
CFTR Gene
gene · KG edge: associated_with
casp3
gene · KG edge: regulates
CACNA1C Gene
gene · KG edge: associated_with
CACNA1B Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TRPV1 associated_with KCNN4
TRPV1 associated_with KCNQ1
TRPV1 associated_with CACNA1C
TRPV1 associated_with TRPM7
TRPV1 associated_with SCN5A
TRPV1 associated_with PIEZO1
TRPV1 associated_with KCNMA1
TRPV1 associated_with SCN1A
TRPV1 associated_with SCNN1A
TRPV1 associated_with PIEZO2