protein 816 words KG: VPS13D 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

VPS13D Protein

🔬 Protein Info
Gene SymbolVPS13D
Chromosome1p36.22
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight500 kDa
Amino Acids377 aa
Exons76
GeneCardsVPS13D
Human Protein AtlasVPS13D
Associated DiseasesMs, Parkinson
InteractionsPARKIN, UBIQUITIN, STING
KG Connections18 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Validate Mitochondria-Lysosome Contact Site Dysfunction in P
validation · proposed · Score: 0.40

See Also (12)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: associated_with
Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: associated_with
VPS35 — Vacuolar Protein Sorting 35 Homolog
gene · KG edge: associated_with
VPS11 — Vacuolar Protein Sorting 11
gene · KG edge: associated_with
PIK3C3 — Phosphatidylinositol 3-Kinase Catalytic Subuni
gene · KG edge: associated_with

Knowledge Graph (12 edges)

VPS13D associated_with GBA
VPS13D associated_with VPS11
VPS13D associated_with PIK3C3
VPS13D associated_with LRRK2
VPS13D interacts_with PARKIN
VPS13D interacts_with UBIQUITIN
VPS13D activates neuroinflammation
VPS13D associated_with GENES
VPS13D associated_with Parkinson
VPS13D associated_with Ms