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PTBP1 Gene

🧬 Gene Info

Gene Symbol	PTBP1
Full Name	Polypyrimidine Tract Binding Protein 1
Chromosome	19p13.3.
Function	is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of RNA-binding proteins.
Primary Expression	neural progenitor cells and declines as neurons differentiate
Subcellular Localization	### Transcriptional Regulation
Molecular Weight	57 kDa
Amino Acids	531 aa
Exons	15
Pathways	Autophagy, Epigenetic, Glycolysis, Innate Immunity, Stem Cell
Ensembl ID	ENSG00000064102
GeneCards	PTBP1
Human Protein Atlas	PTBP1
Promoter elements	Contains binding sites for REST, neuron-restrictive silencer factor
Alternative promoters	Multiple TSS give rise to isoforms with different N-termini
Associated Diseases	Als
Interactions	ATG, ATG10, ATG5, AUTOPHAGY, CALCOCO2, CANCER
KG Connections	103 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Knowledge Graph