| Gene Symbol | PTBP1 |
| Full Name | Polypyrimidine Tract Binding Protein 1 |
| Chromosome | 19p13.3. |
| Function | is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of RNA-binding proteins. |
| Primary Expression | neural progenitor cells and declines as neurons differentiate |
| Subcellular Localization | ### Transcriptional Regulation |
| Molecular Weight | 57 kDa |
| Amino Acids | 531 aa |
| Exons | 15 |
| Pathways | Autophagy, Epigenetic, Glycolysis, Innate Immunity, Stem Cell |
| Ensembl ID | ENSG00000064102 |
| GeneCards | PTBP1 |
| Human Protein Atlas | PTBP1 |
| Promoter elements | Contains binding sites for REST, neuron-restrictive silencer factor |
| Alternative promoters | Multiple TSS give rise to isoforms with different N-termini |
| Associated Diseases | Als |
| Interactions | CALCOCO2, EGR1, NDP52, P38, SLC7A11, GPX4 |
| KG Connections | 103 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |