concept

RS6656401

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RS6656401: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

25Outgoing

8Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	RS6656401
Key Genes/Proteins	RS3919533, CLU, CLUSTERIN, CFH, C1S, RS6664877
Related Diseases	Alzheimer, Neurodegeneration
Related Pathways	Complement

Wiki Pages (2)

Knowledge base pages for this entity

CR1 Gene — Complement Component 1q Receptor

gene · 3403 words

→

CR1→Complement Activation→Synaptic Pruning→AD Causal Chain

mechanism · 1179 words

→

Pathway Diagram

graph TD
    RS6656401["RS6656401"]
    RS6656401 -->|"regulates"| CR1["CR1"]
    RS6656401 -->|"implicated in"| RS3919533["RS3919533"]
    RS6656401 -->|"implicated in"| CFH["CFH"]
    RS6656401 -->|"implicated in"| CLU["CLU"]
    RS6656401 -->|"implicated in"| CLUSTERIN["CLUSTERIN"]
    RS6656401 -->|"implicated in"| RS6664877["RS6664877"]
    RS6656401 -->|"implicated in"| C1S["C1S"]

Outgoing (28)

Target	Relation	Type	Str
Alzheimer	associated_with	disease	0.65
Neurodegeneration	associated_with	disease	0.65
RS3919533	associated_with	gene	0.60
CLU	associated_with	gene	0.60
CLUSTERIN	associated_with	gene	0.60
CFH	associated_with	gene	0.60
C1S	associated_with	gene	0.60
RS6664877	associated_with	gene	0.60
GENES	associated_with	gene	0.60
CR1	associated_with	gene	0.60
Complement	associated_with	pathway	0.60
RS3919533	implicated_in	gene	0.60
NEURODEGENERATION	associated_with	gene	0.60
CFH	implicated_in	gene	0.60
CLU	implicated_in	gene	0.60
COMPLEMENT	associated_with	gene	0.60
CR1	implicated_in	gene	0.60
CLUSTERIN	implicated_in	gene	0.60
ALZHEIMER	associated_with	gene	0.60
RS6664877	implicated_in	gene	0.60
AMYLOID	associated_with	gene	0.60
C1Q	associated_with	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
C1S	implicated_in	gene	0.60
Amyloid	associated_with	pathway	0.60

Incoming (9)

Source	Relation	Type	Str
C1Q	associated_with	gene	0.60
CLUSTERIN	associated_with	gene	0.60
RS6664877	associated_with	gene	0.60
AMYLOID	associated_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
AND	associated_with	gene	0.60
GENES	associated_with	gene	0.60
CR1	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found