CLUSTERIN

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLUSTERIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CLUSTERIN is a protein involved in neurodegeneration research. Key relationships include: associated with, regulates, activates. Associated with ALS, Aging, Als. Connected to 115 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    CLUSTERIN["<b>CLUSTERIN</b>"]
    Cancer{"Cancer"}
    CLUSTERIN -->|"regulates"| Cancer
    Neurodegeneration{"Neurodegeneration"}
    CLUSTERIN -->|"associated with"| Neurodegeneration
    Alzheimer{"Alzheimer"}
    CLUSTERIN -->|"associated with"| Alzheimer
    CLUSTERIN -->|"activates"| Alzheimer
    Als{"Als"}
    CLUSTERIN -->|"activates"| Als
    CLUSTERIN -->|"activates"| Cancer
    CLUSTERIN -->|"expressed in"| Alzheimer
    Tumor{"Tumor"}
    CLUSTERIN -->|"expressed in"| Tumor
    Senescence{"Senescence"}
    CLUSTERIN -->|"expressed in"| Senescence
    ALS{"ALS"}
    CLUSTERIN -->|"causes"| ALS
    Parkinson{"Parkinson"}
    CLUSTERIN -->|"causes"| Parkinson
    LC3["LC3"]
    CLUSTERIN -->|"activates"| LC3
    CLU["CLU"]
    CLU -->|"regulates"| CLUSTERIN
    PPARGC1A["PPARGC1A"]
    PPARGC1A -->|"regulates"| CLUSTERIN
    BAX["BAX"]
    BAX -->|"activates"| CLUSTERIN
    C1S["C1S"]
    C1S -->|"regulates"| CLUSTERIN
    PPARG["PPARG"]
    PPARG -->|"regulates"| CLUSTERIN
    CLU -->|"activates"| CLUSTERIN
    CLU -->|"therapeutic target"| CLUSTERIN
    BAX -->|"regulates"| CLUSTERIN
    C1Q["C1Q"]
    C1Q -->|"activates"| CLUSTERIN
    RS6656401["RS6656401"]
    RS6656401 -->|"associated with"| CLUSTERIN
    RS3919533["RS3919533"]
    RS3919533 -->|"associated with"| CLUSTERIN
    BIN1["BIN1"]
    BIN1 -->|"activates"| CLUSTERIN
    style CLUSTERIN fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0