CR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CR1 is a protein involved in neurodegeneration research. Key relationships include: associated with, regulates, co discussed. Associated with ALS, Aging, Als. Connected to 128 entities in the SciDEX knowledge graph.

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graph TD
    CR1["<b>CR1</b>"]
    Amyloid_beta_42["Amyloid-beta 42"]
    CR1 -->|"regulates"| Amyloid_beta_42
    complement_receptor_1["complement receptor 1"]
    CR1 -->|"encodes"| complement_receptor_1
    Neurodegeneration{"Neurodegeneration"}
    CR1 -->|"associated with"| Neurodegeneration
    Multiple_Sclerosis{"Multiple Sclerosis"}
    CR1 -->|"associated with"| Multiple_Sclerosis
    Als{"Als"}
    CR1 -->|"associated with"| Als
    Aging{"Aging"}
    CR1 -->|"associated with"| Aging
    Ms{"Ms"}
    CR1 -->|"associated with"| Ms
    Alzheimer{"Alzheimer"}
    CR1 -->|"associated with"| Alzheimer
    MICROGLIA["MICROGLIA"]
    CR1 -->|"associated with"| MICROGLIA
    SYNAPSE["SYNAPSE"]
    CR1 -->|"associated with"| SYNAPSE
    TAU["TAU"]
    CR1 -->|"associated with"| TAU
    Dementia{"Dementia"}
    CR1 -->|"associated with"| Dementia
    rs6656401["rs6656401"]
    rs6656401 -->|"regulates"| CR1
    APP["APP"]
    APP -->|"associated with"| CR1
    CLU["CLU"]
    CLU -->|"associated with"| CR1
    C1QA["C1QA"]
    C1QA -->|"associated with"| CR1
    CLU -->|"regulates"| CR1
    C1S["C1S"]
    C1S -->|"associated with"| CR1
    CLUSTERIN["CLUSTERIN"]
    CLUSTERIN -->|"regulates"| CR1
    C1Q["C1Q"]
    C1Q -->|"regulates"| CR1
    GENES["GENES"]
    GENES -->|"associated with"| CR1
    RS6656401["RS6656401"]
    RS6656401 -->|"associated with"| CR1
    RS3919533["RS3919533"]
    RS3919533 -->|"associated with"| CR1
    CFH["CFH"]
    CFH -->|"associated with"| CR1
    style CR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0