gene 1,058 words KG: SLC1A5
Contents

SLC1A5 Gene

🧬 Gene Info
Gene SymbolSLC1A5
Full NameSolute Carrier Family 1 Member 5
Chromosome19q13.33
Protein TypeTransporter
Functionis a sodium-dependent neutral amino acid transporter critical for cellular uptake of glutamine, alanine, serine, and cysteine[@amino2017].
Primary Expressionmany cancers where it supports rapid glutamine metabolism[@slc2020]
Molecular Weight56 kDa
Amino Acids541 aa
PathwaysmTOR pathway
UniProt IDP52802
NCBI Gene ID6510
Ensembl IDENSG00000105374
OMIM109440
GeneCardsSLC1A5
Human Protein AtlasSLC1A5
Associated Diseasesneurodegeneration
InteractionsACC, ACLY, AUTOPHAGY, CANCER, DNA, DYRK1A
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

SLC1A5 activates MYC
STAT3 regulates SLC1A5
SLC1A5 regulates MYC
SLC1A5 regulates MTOR
SLC1A5 inhibits Rb
FASN activates SLC1A5
GLS activates SLC1A5
HK2 activates SLC1A5
DYRK1A inhibits SLC1A5
SLC1A5 inhibits SMAD3

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