gene 1,589 words KG: SPG11
Contents

SPG11 Gene - Spastic Paraplegia 11

🧬 Gene Info
Gene SymbolSPG11
AliasesPage for SPG11 Gene
Chromosome10p14
Functionis a large cytoplasmic protein encoded by the SPG11 gene located on chromosome 15q21.
Primary ExpressionPredominantly neuronal
Molecular Weight250 kDa
Amino Acids163 aa
Exons40
UniProt IDQ96MC7
NCBI Gene ID80208
GeneCardsSPG11
Human Protein AtlasSPG11
Central nervous systemCerebral cortex, hippocampus, basal ganglia, thalamus, cerebellum
Spinal cordMotor neurons, interneurons
Peripheral nervous systemDorsal root ganglia
Associated DiseasesInflammation, neurodegeneration, Neuroinflammation
InteractionsMICROGLIA, NEURODEGENERATION
KG Connections30 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

SPG11 associated_with SPG15
ALS2 associated_with SPG11
ANG associated_with SPG11
DAO associated_with SPG11
DCTN1 associated_with SPG11
FIG4 associated_with SPG11
FUS associated_with SPG11
NEFH associated_with SPG11
OPTN associated_with SPG11
SETX associated_with SPG11

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