gene 909 words KG: NEFH 2026-03-24
kind:genesection:genesstate:published
Contents

NEFH — Neurofilament Heavy Chain

🧬 Gene Info
Gene SymbolNEFH
Full NameNeurofilament Heavy Chain
Chromosome22q12.1
FunctionNeurofilament Heavy Chain (NF-H) is the largest neurofilament subunit (approximately 200 kDa) and plays critical roles in neuronal biology
Primary ExpressionLarge motor neurons, sensory neurons, brain (cortex, hippocampus, cerebellum)
Molecular Weight200 kDa
Amino Acids816 aa
Exons4
UniProt IDP06744
NCBI Gene ID4744
Ensembl IDENSG00000100133
OMIM162400
GeneCardsNEFH
Human Protein AtlasNEFH
Associated DiseasesAging, Als, Alzheimer, Inflammation, Ms, Neurodegeneration
InteractionsKIF5B, PVALB, AKT1, RANK, P53, AGING
KG Connections96 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph