gene 532 words KG: SUMO1
Contents

SUMO1 — Small Ubiquitin-Like Modifier 1

🧬 Gene Info
Gene SymbolSUMO1
Full NameSmall Ubiquitin-Like Modifier 1
AliasesPage for SUMO1 Protein
Chromosome2q33
FunctionSUMO1 encodes a small ubiquitin-like protein (~101 amino acids) that can be covalently attached to lysine residues in target proteins through an enzymatic cascade involving E1, E2, and E3 enzymes.
Primary ExpressionUbiquitous - High in brain, heart, liver
Molecular Weight11.6 kDa
Amino Acids101 aa
UniProt IDP63165
NCBI Gene ID7341
Ensembl IDENSG00000116030
OMIM601561
GeneCardsSUMO1
Human Protein AtlasSUMO1
Associated DiseasesAls
InteractionsATG12, ATG5, ATG7, HIF1A, LC3, MFN1
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

SUMO1-Mediated Synaptotagmin-1 SUMOylation at Lys124 Impairs
Score: 0.65

Knowledge Graph (12 edges)

SUMO1 interacts_with RANBP2
RANBP2 interacts_with SUMO1
MFN1 inhibits SUMO1
SENP1 activates SUMO1
UBIQUITIN inhibits SUMO1
NRF1 inhibits SUMO1
OPA1 inhibits SUMO1
MFN2 inhibits SUMO1
TFAM inhibits SUMO1
SIRT1 inhibits SUMO1

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