| Gene Symbol | NRF1 |
| Chromosome | 5q31.1 |
| Protein Type | Gene |
| Function | NRF1 is a critical transcription factor that coordinates the expression of genes involved in mitochondrial function and cellular respiration: [@srensen2020] |
| Primary Expression | tissues with high energy demands: |
| Pathways | Apoptosis, Autophagy, Chaperone, Cholesterol, Differentiation |
| GeneCards | NRF1 |
| Human Protein Atlas | NRF1 |
| Associated Diseases | Aging, Als, Alzheimer, Breast Cancer, Cancer |
| Known Drugs/Compounds | nicotinamide, rapamycin |
| Interactions | AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID, AMYLOID-BETA |
| KG Connections | 488 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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