🧫
ALS Regional Onset and Spread: Network-Level Staging Model
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-als-regi
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.905126Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['HNRNPA2B1/SETX/TARDBP'], 'diseases': ['ALS']} |
| model_system | human |
| summary | # ALS Regional Onset and Spread: Network-Level Staging Model ## Background and Rationale Amyotrophic lateral sclerosis (ALS) exhibits remarkably stereotyped patterns of regional onset and systematic s |
| replication_status | single_study |
| methodology_notes | **Phase 1: Multi-Center Patient Recruitment and Clinical Staging (Months 1-12)** • Recruit 500 ALS patients across 10 centers with confirmed diagnosis per El Escorial criteria • Stratify by onset phen |
| primary_outcome | Validate ALS Regional Onset and Spread: Network-Level Staging Model |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.905132'} |
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