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entities-sod1

wiki page Created: 2026-04-02T17:01:41 By: crosslink-v2 Quality: 50% ✓ SciDEX ID: wiki-entities-sod1

Linked Artifacts (133)

mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di75%

mentions🧫s:** - Temporal analysis showing mitochondrial defects prece70%

mentions🧫s:** - Single-cell RNA-seq to measure editing efficiency acr70%

mentions🧫ALS Regional Onset and Spread: Network-Level Staging Model70%

mentions🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des70%

related🧫Cytochrome Therapeutics70%

related🔬CRISPR-based therapeutic approaches for neurodegenerative di67%

related🧫s:** - Temporal analysis showing mitochondrial defects prece63%

related🧫s:** - Single-cell RNA-seq to measure editing efficiency acr63%

related🧫ALS Regional Onset and Spread: Network-Level Staging Model63%

related🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des63%

mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di60%

see_also📖KCNJ10 Gene60%

see_also📖plekhg560%

see_also📖Packard Center for ALS Research60%

see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%

see_also📖Kir4.1 Potassium Channel (KCNJ10)60%

see_also📖PLEKHG5 Protein60%

see_also📖ABCA7 (Redirect)60%

see_also📖ALS10 - Amyotrophic Lateral Sclerosis 10 (TARDBP)60%

see_also📖ALS7 - Amyotrophic Lateral Sclerosis 760%

see_also📖ALS8 - Amyotrophic Lateral Sclerosis 860%

see_also📖ALS9 - Amyotrophic Lateral Sclerosis 960%

see_also📖Alsin (ALSIN)60%

see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%

see_also📖Axonal Degeneration60%

see_also📖Protein Aggregation in Neurodegenerative Disease Comparison60%

see_also📖Alsin Protein (ALS2)60%

see_also📖spinal-cord60%

see_also📖KIF3B — Kinesin Family Member 3B60%

see_also📖sod360%

see_also📖ATP7B60%

see_also📖ACTB Gene60%

see_also📖ACTG1 Gene60%

see_also📖AKT1 Gene60%

see_also📖ATP5A1 Gene60%

see_also📖SEPT7 — Septin 760%

see_also📖Ropinirole - Dopamine Agonist for Parkinson's Disease60%

see_also📖FZD2 Gene60%

see_also📖FZD9 Gene60%

see_also📖C21orf2 — Chromosome 21 Open Reading Frame 260%

see_also📖CHCHD10 — Coiled-Coil-Helix-Coiled-Coil-Helix Domain Contain60%

see_also📖CHCHD10 Protein60%

see_also📖CAMK2D — Calcium/Calmodulin-Dependent Kinase 2 Delta60%

related🧪Circadian-Gated Maresin Biosynthesis Amplification55%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th55%

related🔬CRISPR-based therapeutic approaches for neurodegenerative di54%

mentions🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

mentions🔬What are the mechanisms underlying tdp-43 phase separation t50%

mentions🔬What are the mechanisms underlying astrocyte reactivity subt50%

mentions🔬What are the mechanisms underlying synaptic pruning by micro50%

mentions🔬What are the mechanisms underlying epigenetic clocks and bio50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%

mentions🧪Lysosomal Membrane Repair Enhancement50%

mentions🧪Near-infrared light therapy stimulates COX4-dependent mitoch50%

mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%

mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%

mentions🧪Lysosomal Positioning Dynamics Modulation50%

mentions🧪LRP1-Dependent Tau Uptake Disruption50%

mentions🧪Lysosomal Calcium Channel Modulation Therapy50%

mentions🧪Perforant Path Presynaptic Terminal Protection Strategy50%

mentions🧪AMPK hypersensitivity in astrocytes creates enhanced mitocho50%

mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%

mentions🧪Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli50%

mentions🧪Synaptic Vesicle Tau Capture Inhibition50%

mentions🧪Cryptic Exon Silencing Restoration50%

mentions🧪Cross-Seeding Prevention Strategy50%

mentions🧪Temporal TET2-Mediated Hydroxymethylation Cycling50%

mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering50%

mentions🧪TREM2-mediated microglial tau clearance enhancement50%

mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%

mentions🧪VCP-Mediated Autophagy Enhancement50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

related🔬What are the mechanisms underlying tdp-43 phase separation t50%

related🔬What are the mechanisms underlying astrocyte reactivity subt50%

related🔬What are the mechanisms underlying synaptic pruning by micro50%

related🔬What are the mechanisms underlying epigenetic clocks and bio50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬Cell type vulnerability in Alzheimers Disease (SEA-AD transc50%

related🧪TREM2 Conformational Stabilizers for Synaptic Discrimination40%

related🧪Netrin-1 Gradient Restoration40%

related🧪Purinergic Signaling Polarization Control40%

related🧪Arginine Methylation Enhancement Therapy40%

related🧪Complement C1q Mimetic Decoy Therapy40%

related🧪Metabolic Reprogramming via Microglial Glycolysis Inhibition40%

related🧪SIRT6-NAD+ Axis Enhancement Therapy40%

related🧪Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics40%

related🧪Circadian Rhythm Entrainment of Reactive Astrocytes40%

related🧪Complement C1q Subtype Switching40%

related🧪Microglial Purinergic Reprogramming40%

related🧪Heat Shock Protein 70 Disaggregase Amplification40%

related🧪Sphingolipid Metabolism Reprogramming40%

related🧪PARP1 Inhibition Therapy40%

related🧪Low Complexity Domain Cross-Linking Inhibition40%

related🧪Optogenetic Microglial Deactivation via Engineered Inhibitor40%

related🧪DNMT1-Targeting Antisense Oligonucleotide Reset40%

related🧪Lipid Droplet Dynamics as Phenotype Switches40%

related🧪Glycine-Rich Domain Competitive Inhibition40%

related🧪KDM6A-Mediated H3K27me3 Rejuvenation40%

related🧪Mitochondrial Transfer Pathway Enhancement40%

related🧪Metabolic Switch Targeting for A1→A2 Repolarization40%

related🧪HDAC3-Selective Inhibition for Clock Reset40%

related🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri40%

related🧪Glial Glycocalyx Remodeling Therapy40%

related🧪Aquaporin-4 Polarization Rescue40%

related🧪Epigenetic Memory Erasure via TET2 Activation40%

related🧪TET2-Mediated Demethylation Rejuvenation Therapy40%

related🧪Mechanosensitive Ion Channel Reprogramming40%

related🧪Serine/Arginine-Rich Protein Kinase Modulation40%

related🧪Ephrin-B2/EphB4 Axis Manipulation40%

related🧪Purinergic P2Y12 Inverse Agonist Therapy40%

related🧪FOXO3-Longevity Pathway Epigenetic Reprogramming40%

related🧪RNA Granule Nucleation Site Modulation40%

related🔬What are the mechanisms underlying synaptic pruning by micro40%

related🔬Synaptic pruning by microglia in early AD40%

related🔬What are the mechanisms underlying epigenetic clocks and bio40%

related🔬Epigenetic clocks and biological aging in neurodegeneration40%

related🔬What are the mechanisms underlying tdp-43 phase separation t40%

related🔬TDP-43 undergoes liquid-liquid phase separation that becomes40%

related🔬PSP and CBD both involve 4R-tau but produce distinct neuropa40%

related🔬What are the mechanisms underlying astrocyte reactivity subt40%

related🔬Astrocytes adopt A1 (neurotoxic) and A2 (neuroprotective) ph40%

related🔬CRISPR-based therapeutic approaches for neurodegenerative di40%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp24%