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LGALS3 Gene

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-lgals3
Related Entities
LGALS3
Metadata
sluggenes-lgals3
entity_typegene
kg_node_idLGALS3
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (112)
mentions🧪Liquid-Liquid Phase Separation Modifier Therapy70%
related🧪Liquid-Liquid Phase Separation Modifier Therapy63%
related🧫s:** - Single-cell RNA-seq to measure editing efficiency acr60%
related🧫Metabolic Pathway-Targeted Therapy in ALS60%
related🧫ALS Progression Rate Heterogeneity — mechanism and biomarker60%
related🧫ALS Regional Onset and Spread: Network-Level Staging Model60%
related🧫Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk60%
related🧫Anti-Tau Therapy Failure Mechanism in PSP — Why Clinical Tri60%
related🧫Blood Biomarker vs Tau PET for Treatment Monitoring60%
related🧫Brainstem Circuit Modulation for PSP60%
related🧫Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT60%
related🧫C9orf72 Phenotype Divergence: ALS vs FTD Mechanism Study60%
related🧫Environmental Exposure Causal Attribution in ALS — Experimen60%
related🧫FXTAS Phenotypic Penetrance: Why Only 40% of FMR1 Premutatio60%
related🧫Microbiome-Gut Barrier Signatures in ALS — Experiment Design60%
related🧫N-of-1 Clinical Trial Design for CBS/PSP60%
related🧫Pre-Symptomatic Tau Detection in MAPT Mutation Carriers60%
related🧫Pre-Symptomatic Detection and Intervention Timing in Genetic60%
related🧫Progranulin Replacement Therapy for FTD — Vector Development60%
related🧫Mechanism: Progranulin Loss and TDP-43 Pathology in FTD60%
related🧫PSP and CBS Biomarker Validation Study60%
related🧫Sleep and Respiratory Network Interaction in ALS — Experimen60%
related🧫TDP-43 PET Ligand Development for FTD and ALS60%
related🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des60%
see_also📖AMPK (AMP-Activated Protein Kinase)60%
see_also📖RGS1 — Regulator of G Protein Signaling 160%
see_also📖Alzheimer Indonesia60%
see_also📖Packard Center for ALS Research60%
see_also📖APOA2 Gene60%
see_also📖CSNK2A1 Gene60%
see_also📖NME1 - NME Nucleoside Diphosphate Kinase 160%
see_also📖STX4 — Syntaxin-460%
see_also📖Actin Cytoskeleton Dynamics in Neurodegeneration60%
see_also📖SLC9A1 — Sodium/Hydrogen Exchanger 160%
see_also📖SESN3 Gene60%
see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%
see_also📖TCF7L2 (Transcription Factor 7-Like 2)60%
see_also📖ABCD3 Gene60%
see_also📖ambra160%
see_also📖adam1060%
see_also📖RPS6KA1 — Ribosomal Protein S6 Kinase A160%
see_also📖TTR — Transthyretin60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
related🧫s:** - Single-cell RNA-seq to measure editing efficiency acr54%
related🧫Metabolic Pathway-Targeted Therapy in ALS54%
related🧫ALS Progression Rate Heterogeneity — mechanism and biomarker54%
related🧫ALS Regional Onset and Spread: Network-Level Staging Model54%
related🧫Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk54%
related🧫Anti-Tau Therapy Failure Mechanism in PSP — Why Clinical Tri54%
related🧫Blood Biomarker vs Tau PET for Treatment Monitoring54%
related🧫Brainstem Circuit Modulation for PSP54%
related🧫Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT54%
related🧫C9orf72 Phenotype Divergence: ALS vs FTD Mechanism Study54%
related🧫Environmental Exposure Causal Attribution in ALS — Experimen54%
related🧫FXTAS Phenotypic Penetrance: Why Only 40% of FMR1 Premutatio54%
related🧫Microbiome-Gut Barrier Signatures in ALS — Experiment Design54%
related🧫N-of-1 Clinical Trial Design for CBS/PSP54%
related🧫Pre-Symptomatic Tau Detection in MAPT Mutation Carriers54%
related🧫Pre-Symptomatic Detection and Intervention Timing in Genetic54%
related🧫Progranulin Replacement Therapy for FTD — Vector Development54%
related🧫Mechanism: Progranulin Loss and TDP-43 Pathology in FTD54%
related🧫PSP and CBS Biomarker Validation Study54%
related🧫Sleep and Respiratory Network Interaction in ALS — Experimen54%
related🧫TDP-43 PET Ligand Development for FTD and ALS54%
related🧫Viral and Post-Infectious Mechanisms in ALS — Experiment Des54%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Optogenetic Microglial Deactivation via Engineered Inhibitor50%
mentions🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri50%
mentions🧪FOXO3-Longevity Pathway Epigenetic Reprogramming50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪Phase-Separated Organelle Targeting50%
mentions🧪RNA Granule Nucleation Site Modulation50%
mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
mentions🧪Metabolic Reprogramming via Microglial Glycolysis Inhibition50%
mentions🧪Metabolic Switch Targeting for A1→A2 Repolarization50%
mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%
mentions🧪Lysosomal Positioning Dynamics Modulation50%
mentions🧪Lysosomal Calcium Channel Modulation Therapy50%
mentions🧪Mitochondrial Transfer Pathway Enhancement50%
mentions🧪Perforant Path Presynaptic Terminal Protection Strategy50%
mentions🧪Cryptic Exon Silencing Restoration50%
mentions🧪Glycine-Rich Domain Competitive Inhibition50%
mentions🧪Cross-Seeding Prevention Strategy50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪APOE-TREM2 Interaction Modulation50%
mentions🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%
mentions🧪TREM2-Dependent Microglial Senescence Transition50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
related🧪Liquid-Liquid Phase Separation Modifier Therapy50%
related🔬What are the mechanisms underlying tdp-43 phase separation t50%
related🔬What are the mechanisms underlying astrocyte reactivity subt50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪CYP46A1 Overexpression Gene Therapy40%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%
mentions🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas35%
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